IGF2-BP2 Polyclonal Antibody, 50ul Culture Plate Inserts MIM 176915)

MIM 176915)

Mutations in KRT8 cause cryptogenic cirrhosis

Interacts with subunit of G(i) alpha proteins and regulates the activation of G(i) alpha proteins

The interactions with cytoskeletal proteins and a kinase substrate suggest a role for this protein in vesicular trafficking or organelle transport

Mutations in this gene are correlated with gastric

IGF2-BP2 Polyclonal Antibody, 50ul Culture Plate Inserts MIM 176915)IGF2BP2 encodes a member of the IGF II mRNA binding protein (IMP) family. The insulin like growth factor 2 mRNA binding protein 2 encoded by this gene contains four KH domains and two RRM domains. It functions by binding to the 5' UTR of the insulin like growth factor 2 (IGF2) mRNA and regulating IGF2 translation. Alternative promoter usage and alternate splicing result in multiple variants encoding different isoforms.